Protection Provided by Hepatitis B Vaccine in Adult Population of Chaharmahal and Bakhtiari Province, Iran in 2013
Introduction: Hepatitis B vaccination has been integrated into National Expanded Program on Immunization in Iran since the year 1993 and young adult national vaccination project was done in 2008. So we have three subpopulations with vaccination coverage for hepatitis B and different antibody leve...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7548/17758_CE(RA1)_F(T)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Introduction: Hepatitis B vaccination has been integrated into
National Expanded Program on Immunization in Iran since the
year 1993 and young adult national vaccination project was
done in 2008. So we have three subpopulations with vaccination coverage for hepatitis B and different antibody levels.
Consisting of Subpopulation 1 born after 1993, subpopulation
2 born between 1989 and 1993 and receiving vaccination under
adult national project, and subpopulation 3 born prior to the year
1989.
Aim: The present study was conducted to investigate
community protection by hepatitis B vaccine in adult population
in an accessible population in Iran and compare vaccination
coverage, HBs Ab level, and its effective titration among the
three above-mentioned subpopulations.
Materials and Methods: This cross-sectional study was done
on a 3000-individual adult population from all seven counties
of Chaharmahal and Bakhtiari province enrolled by clustering.
After obtaining written consent and filling out a questionnaire
of demographic data and history of hepatitis B vaccination by
trained interviewers, necessary blood sample was taken and
HBs Ab titration was checked. The data were analysed by
chi-square in SPSS 19. The level of significance was considered
as 0.05 and effective Ab titration as ≥ 10.
Results: The mean age of the participants was 38.4±16.3
years. Of the participants 48.2% had effective titration.
For vaccination coverage, 77.4% were unvaccinated, 20%
completely vaccinated, and 2.6% incompletely vaccinated with
a significant association with effective titration (p<0.001). Eighty
six percent of the subpopulation 1 and 79% of the subpopulation
2 were completely vaccinated, with a significant difference
in effective titration between them (p<0.001). Vaccination
coverage was higher in men and the single but equal in cities
and villages. The effective titration was significantly associated
with being married and residence place (p=0.003). There was a
significant association between effective titration and the time
at vaccination (p<0.001).
Conclusion: Protection provided by hepatitis B vaccine in
adult population is relatively suitable especially in the youth
population; however, catch-up programs of the groups exposed
to risk are recommended. |
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| ISSN: | 2249-782X 0973-709X |