Multi-scale phase separation by explosive percolation with single-chromatin loop resolution

Multi-scale phase separation by explosive percolation with single-chromatin loop resolution

The 2 m-long human DNA is tightly intertwined into the cell nucleus of the size of 10 μm. The DNA packing is explained by folding of chromatin fiber. This folding leads to the formation of such hierarchical structures as: chromosomal territories, compartments; densely-packed genomic regions known as...

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Bibliographic Details
Main Authors: Kaustav Sengupta, Michał Denkiewicz, Mateusz Chiliński, Teresa Szczepińska, Ayatullah Faruk Mollah, Sevastianos Korsak, Raissa D'Souza, Yijun Ruan, Dariusz Plewczynski
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
3D genomics
Percolation
Phase separation
Chromatin folding
Networks
Scalar parameter
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702200277X

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