Ipriflavone attenuates the degeneration of cartilage by blocking the Indian hedgehog pathway
Abstract Background To determine if ipriflavone, a novel and safe inhibitor of Indian hedgehog (Ihh) signaling, can attenuate cartilage degeneration by blocking the Ihh pathway. Methods Human chondrocytes were used to evaluate Ihh signaling, cell proliferation, apoptosis, gene, and protein expressio...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-05-01
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| Series: | Arthritis Research & Therapy |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13075-019-1895-x |