RhoA balances microglial reactivity and survival during neuroinflammation
Abstract Microglia are the largest myeloid cell population in the brain. During injury, disease, or inflammation, microglia adopt different functional states primarily involved in restoring brain homeostasis. However, sustained or exacerbated microglia inflammatory reactivity can lead to brain damag...
Main Authors: | Renato Socodato, Artur Rodrigues-Santos, Joana Tedim-Moreira, Tiago O. Almeida, Teresa Canedo, Camila C. Portugal, João B. Relvas |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-06217-w |
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