Alu antisense RNA ameliorates methylglyoxal-induced human lens epithelial cell apoptosis by enhancing antioxidant defense

Alu antisense RNA ameliorates methylglyoxal-induced human lens epithelial cell apoptosis by enhancing antioxidant defense

AIM: To determine whether an antisense RNA corresponding to the human Alu transposable element (Aluas RNA) can protect human lens epithelial cells (HLECs) from methylglyoxal-induced apoptosis. METHODS: Cell counting kit-8 (CCK-8) and 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)...

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Bibliographic Details
Main Authors: Pei-Yuan Wu, Ning Ji, Chong-Guang Wu, Xiao-Die Wang, Xin Liu, Zhi-Xue Song, Murad Khan, Suleman Shah, Ying-Hua Du, Xiu-Fang Wang, Li-Fang Yan
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2023-02-01
Series:International Journal of Ophthalmology
Subjects:
human alu antisense rna
human lens epithelial cells
methylglyoxal toxicity
antioxidant defense
apoptosis
Online Access:http://ies.ijo.cn/en_publish/2023/2/20230203.pdf

Internet

http://ies.ijo.cn/en_publish/2023/2/20230203.pdf

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