A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits activation of the classical complement pathway
ABSTRACTStreptococcus equi subsp. zooepidemicus (SEZ) is a major equine pathogen that causes pneumonia, abortion, and polyarthritis. It can also cause invasive infections in humans. SEZ expresses the M-like protein SzM, which recruits host proteins such as fibrinogen to the bacterial surface. Equine...
Main Authors: | René Bergmann, Wieland Schroedl, Uwe Müller, Christoph Georg Baums |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
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Series: | Virulence |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/21505594.2023.2235461 |
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