A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture

Abstract In this study, a surface plasmon resonance sensor for detecting haemoglobin concentration based on a D‐type optical fibre with a graphene‐gold surface architecture is proposed. The graphene‐gold surface architecture included a 50 nm thick gold film and monolayer graphene film, which were de...

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Main Authors: Zhen‐Jiang Shi, Shi‐Liang Guo, Xin Li, Wen‐Chao Li, Zhi‐Quan Li
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:IET Optoelectronics
Subjects:
Online Access:https://doi.org/10.1049/ote2.12092
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author Zhen‐Jiang Shi
Shi‐Liang Guo
Xin Li
Wen‐Chao Li
Zhi‐Quan Li
author_facet Zhen‐Jiang Shi
Shi‐Liang Guo
Xin Li
Wen‐Chao Li
Zhi‐Quan Li
author_sort Zhen‐Jiang Shi
collection DOAJ
description Abstract In this study, a surface plasmon resonance sensor for detecting haemoglobin concentration based on a D‐type optical fibre with a graphene‐gold surface architecture is proposed. The graphene‐gold surface architecture included a 50 nm thick gold film and monolayer graphene film, which were decorated on a 10 mm long D‐type sensing region. The proposed sensor worked in wavelength interrogation mode, with the light wavelength ranging from 400 to 1100 nm. The authors realised the D‐type optical fibre surface polishing process, the gold film vacuum coating process, and the chemical‐vapour‐deposited graphene's wet transfer process. Furthermore, the fabricated sensors were used to detect the refractive index (RI) of haemoglobin samples, which varied from 1.331 to 1.346. Experiment results show that the fitted RI sensitivity of the sensor decorated with gold and graphene reaches 1874.41 nm/RIU, 4.995% higher than that of the sensor decorated only with gold. The concentration sensitivity of the sensor coated with gold and graphene film is 4.96 nm/(g/dL), and the proposed sensor can provide a resolution of 20.2 mg/dL for haemoglobin concentration detection.
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spelling doaj.art-399be22ce3bd42998c0be0f7f80aac9d2023-10-13T04:21:01ZengWileyIET Optoelectronics1751-87681751-87762023-10-0117519520110.1049/ote2.12092A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architectureZhen‐Jiang Shi0Shi‐Liang Guo1Xin Li2Wen‐Chao Li3Zhi‐Quan Li4Engineering Research Center of the Ministry of Education for Intelligent Control System and Intelligent Equipment Yanshan University Qinhuangdao ChinaEngineering Research Center of the Ministry of Education for Intelligent Control System and Intelligent Equipment Yanshan University Qinhuangdao ChinaSchool of Mathematics & Information Technology Hebei Normal University of Science & Technology Qinhuangdao ChinaSchool of Control Engineering Northeastern University at Qinhuangdao Qinhuangdao ChinaEngineering Research Center of the Ministry of Education for Intelligent Control System and Intelligent Equipment Yanshan University Qinhuangdao ChinaAbstract In this study, a surface plasmon resonance sensor for detecting haemoglobin concentration based on a D‐type optical fibre with a graphene‐gold surface architecture is proposed. The graphene‐gold surface architecture included a 50 nm thick gold film and monolayer graphene film, which were decorated on a 10 mm long D‐type sensing region. The proposed sensor worked in wavelength interrogation mode, with the light wavelength ranging from 400 to 1100 nm. The authors realised the D‐type optical fibre surface polishing process, the gold film vacuum coating process, and the chemical‐vapour‐deposited graphene's wet transfer process. Furthermore, the fabricated sensors were used to detect the refractive index (RI) of haemoglobin samples, which varied from 1.331 to 1.346. Experiment results show that the fitted RI sensitivity of the sensor decorated with gold and graphene reaches 1874.41 nm/RIU, 4.995% higher than that of the sensor decorated only with gold. The concentration sensitivity of the sensor coated with gold and graphene film is 4.96 nm/(g/dL), and the proposed sensor can provide a resolution of 20.2 mg/dL for haemoglobin concentration detection.https://doi.org/10.1049/ote2.12092biosensorsfibre optic sensorsgraphenemetallic thin filmsnanofabricationoptical films
spellingShingle Zhen‐Jiang Shi
Shi‐Liang Guo
Xin Li
Wen‐Chao Li
Zhi‐Quan Li
A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
IET Optoelectronics
biosensors
fibre optic sensors
graphene
metallic thin films
nanofabrication
optical films
title A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
title_full A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
title_fullStr A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
title_full_unstemmed A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
title_short A surface plasmon resonance haemoglobin concentration sensor based on D‐type optical fibre with a graphene‐gold surface architecture
title_sort surface plasmon resonance haemoglobin concentration sensor based on d type optical fibre with a graphene gold surface architecture
topic biosensors
fibre optic sensors
graphene
metallic thin films
nanofabrication
optical films
url https://doi.org/10.1049/ote2.12092
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