Urinary dipeptidyl peptidase-4 is a useful marker for tubulitis, and it is released from the tubular cells of kidney transplant recipients

Urinary dipeptidyl peptidase-4 is a useful marker for tubulitis, and it is released from the tubular cells of kidney transplant recipients

Abstract Background Biomarkers are needed to diagnose kidney rejection in transplant recipients. We evaluated whether dipeptidyl peptidase-4 (DPP-4) could serve as a biomarker of rejection. Methods We determined DPP-4 concentrations and enzymatic activities in serum and urine, as well as DPP-4 expre...

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Bibliographic Details
Main Authors: Atsushi Yamagishi, Hayato Nishida, Hiromi Ito, Hiroki Fukuhara, Norihiko Tsuchiya
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Renal Replacement Therapy
Subjects:
DPP-4
Marker
Kidney transplantation
Tubulitis
Urine
Rejection
Online Access:https://doi.org/10.1186/s41100-022-00421-8

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