Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists.
To facilitate longer duration space travel, flight crew sickness and disease transmission amongst the crew must be eliminated. High contact surfaces within space vehicles provide an opportunity for bacterial adhesion, which can lead to biofilm formation or disease transmission. This study evaluates...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0261817 |
| _version_ | 1819003598406680576 |
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| author | Niko Hansen Adriana Bryant Roslyn McCormack Hannah Johnson Travis Lindsay Kael Stelck Matthew T Bernards |
| author_facet | Niko Hansen Adriana Bryant Roslyn McCormack Hannah Johnson Travis Lindsay Kael Stelck Matthew T Bernards |
| author_sort | Niko Hansen |
| collection | DOAJ |
| description | To facilitate longer duration space travel, flight crew sickness and disease transmission amongst the crew must be eliminated. High contact surfaces within space vehicles provide an opportunity for bacterial adhesion, which can lead to biofilm formation or disease transmission. This study evaluates the performance of several nonfouling polymers using citizen science, to identify the best performing chemistry for future applications as bacteria resistant coatings. The specific polymer chemistries tested were zwitterionic sulfobetaine methacrylate (SBMA), and polyampholytes composed of [2-(acryloyloxy)ethyl] trimethylammonium chloride and 2-carboxyethyl acrylate (TMA/CAA), or TMA and 3-sulfopropyl methacrylate (TMA/SA). Each polymer chemistry is known to exhibit bacteria resistance, and this study provides a direct side-by-side comparison between the chemistries using a citizen science approach. Nearly 100 citizen scientists returned results comparing the performance of these polymers over repeat exposure to bacteria and 30 total days of growth. The results demonstrate that TMA/CAA polyampholyte hydrogels show the best long-term resistance to bacteria adhesion. |
| first_indexed | 2024-12-20T23:23:33Z |
| format | Article |
| id | doaj.art-399f9be6453744b699930630df4256c1 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T23:23:33Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-399f9be6453744b699930630df4256c12022-12-21T19:23:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011612e026181710.1371/journal.pone.0261817Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists.Niko HansenAdriana BryantRoslyn McCormackHannah JohnsonTravis LindsayKael StelckMatthew T BernardsTo facilitate longer duration space travel, flight crew sickness and disease transmission amongst the crew must be eliminated. High contact surfaces within space vehicles provide an opportunity for bacterial adhesion, which can lead to biofilm formation or disease transmission. This study evaluates the performance of several nonfouling polymers using citizen science, to identify the best performing chemistry for future applications as bacteria resistant coatings. The specific polymer chemistries tested were zwitterionic sulfobetaine methacrylate (SBMA), and polyampholytes composed of [2-(acryloyloxy)ethyl] trimethylammonium chloride and 2-carboxyethyl acrylate (TMA/CAA), or TMA and 3-sulfopropyl methacrylate (TMA/SA). Each polymer chemistry is known to exhibit bacteria resistance, and this study provides a direct side-by-side comparison between the chemistries using a citizen science approach. Nearly 100 citizen scientists returned results comparing the performance of these polymers over repeat exposure to bacteria and 30 total days of growth. The results demonstrate that TMA/CAA polyampholyte hydrogels show the best long-term resistance to bacteria adhesion.https://doi.org/10.1371/journal.pone.0261817 |
| spellingShingle | Niko Hansen Adriana Bryant Roslyn McCormack Hannah Johnson Travis Lindsay Kael Stelck Matthew T Bernards Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. PLoS ONE |
| title | Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. |
| title_full | Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. |
| title_fullStr | Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. |
| title_full_unstemmed | Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. |
| title_short | Assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists. |
| title_sort | assessment of the performance of nonfouling polymer hydrogels utilizing citizen scientists |
| url | https://doi.org/10.1371/journal.pone.0261817 |
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