Pharmacological modulation of anti-tumor immunity induced by oncolytic viruses

Pharmacological modulation of anti-tumor immunity induced by oncolytic viruses

Oncolytic viruses kill cancer cells by direct lysis but also generate a significant anti-tumor immune response that allows for prolonged cancer control and in some cases cures. How to best stimulate this effect is a subject of intense investigation in the oncolytic virus field. While pharmacological...

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Bibliographic Details
Main Authors: Nicole E. Forbes, Ramya eKrishnan, Jean-Simon eDiallo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Oncology
Subjects:
Oncolytic Virotherapy
Cancer
chemotherapy
combination therapy
anti-tumor immunity
Immunomodulatory therapy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00191/full

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