Integrated multi-omics analysis reveals the positive leverage of citrus flavonoids on hindgut microbiota and host homeostasis by modulating sphingolipid metabolism in mid-lactation dairy cows consuming a high-starch diet

Integrated multi-omics analysis reveals the positive leverage of citrus flavonoids on hindgut microbiota and host homeostasis by modulating sphingolipid metabolism in mid-lactation dairy cows consuming a high-starch diet

Abstract Background Modern dairy diets have shifted from being forage-based to grain and energy dense. However, feeding high-starch diets can lead to a metabolic disturbance that is linked to dysregulation of the gastrointestinal microbiome and systemic inflammatory response. Plant flavonoids have r...

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Bibliographic Details
Main Authors: Yuchao Zhao, Shiqiang Yu, Huiying Zhao, Liuxue Li, Yuqin Li, Ming Liu, Linshu Jiang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Microbiome
Subjects:
Dairy cows
Metaproteomics
Hindgut fermentation
Systemic inflammation
Sphingolipid metabolism
Online Access:https://doi.org/10.1186/s40168-023-01661-4

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