A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity
Hepatic lipase (HL) is a lipolytic enzyme involved in the metabolism of plasma lipoproteins, especially HDLs. Association of the polymorphisms in the promoter region of the LIPC gene to post-heparin plasma HL activity and the plasma HDL-C concentration has been investigated thoroughly, but to date l...
Main Authors: | Zhiguang Su, Sizhong Zhang, Daniel W. Nebert, Li Zhang, Dejia Huang, Yiping Hou, Linchuan Liao, Cuiying Xiao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2002-10-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520327784 |
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