Tick-borne encephalitis in children

The purpose of the study is to characterize the clinical and epidemiological indicators of the acute period of tick-borne encephalitis (TBE) in children who became ill in 1990—2017 and living in the region of Siberia and the Far East.We presented clinical and epidemiological data on TBE. The diagnos...

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Main Authors: A. P. Pomogaeva, М. О. Karavaeva
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2019-07-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/419
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author A. P. Pomogaeva
М. О. Karavaeva
author_facet A. P. Pomogaeva
М. О. Karavaeva
author_sort A. P. Pomogaeva
collection DOAJ
description The purpose of the study is to characterize the clinical and epidemiological indicators of the acute period of tick-borne encephalitis (TBE) in children who became ill in 1990—2017 and living in the region of Siberia and the Far East.We presented clinical and epidemiological data on TBE. The diagnosis  of TBE was confirmed by Hemagglutination inhibition reaction, ELISA test and PCR. Other tick-borne diseases and diseases with similar symptoms were excluded. It was mathematically proved that incidence rate depends on the increase in tick populations and duration of epidemic season but not on their virus activity.A significant reduction in the incidence rate and a change in the ratio of clinical forms were recorded after 2003. The frequency of a febrile form increased, while the frequency of meningeal and focal forms decreased without change in frequency and severity of TBE symptoms. The threat of a fatal outcome persists, which can only be prevented by early diagnosis, adequate therapy and vaccination.
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spelling doaj.art-39a6d95a6c504d11b46cdbcb565033832025-03-05T13:50:44ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072019-07-01182171910.22627/2072-8107-2019-18-2-17-19391Tick-borne encephalitis in childrenA. P. Pomogaeva0М. О. Karavaeva1Siberian State Medical UniversityChildren’s Hospital №1The purpose of the study is to characterize the clinical and epidemiological indicators of the acute period of tick-borne encephalitis (TBE) in children who became ill in 1990—2017 and living in the region of Siberia and the Far East.We presented clinical and epidemiological data on TBE. The diagnosis  of TBE was confirmed by Hemagglutination inhibition reaction, ELISA test and PCR. Other tick-borne diseases and diseases with similar symptoms were excluded. It was mathematically proved that incidence rate depends on the increase in tick populations and duration of epidemic season but not on their virus activity.A significant reduction in the incidence rate and a change in the ratio of clinical forms were recorded after 2003. The frequency of a febrile form increased, while the frequency of meningeal and focal forms decreased without change in frequency and severity of TBE symptoms. The threat of a fatal outcome persists, which can only be prevented by early diagnosis, adequate therapy and vaccination.https://detinf.elpub.ru/jour/article/view/419childrentick-borne encephalitisepidemiologyclinical pictureoutcomes
spellingShingle A. P. Pomogaeva
М. О. Karavaeva
Tick-borne encephalitis in children
Детские инфекции (Москва)
children
tick-borne encephalitis
epidemiology
clinical picture
outcomes
title Tick-borne encephalitis in children
title_full Tick-borne encephalitis in children
title_fullStr Tick-borne encephalitis in children
title_full_unstemmed Tick-borne encephalitis in children
title_short Tick-borne encephalitis in children
title_sort tick borne encephalitis in children
topic children
tick-borne encephalitis
epidemiology
clinical picture
outcomes
url https://detinf.elpub.ru/jour/article/view/419
work_keys_str_mv AT appomogaeva tickborneencephalitisinchildren
AT mokaravaeva tickborneencephalitisinchildren