IgG4-Related Disease: A Concise Review
IgG4-related disease (IgG4-RD) is a multi-organ fibroinflammatory disorder that may result in organ dysfunction and complications. Glucocorticoids remain the primary treatment for inducing remission, while recently reported disease phenotypes might inform personalized therapeutic strategies. Progres...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
World Scientific Publishing
2023-07-01
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| Series: | Journal of Clinical Rheumatology and Immunology |
| Subjects: | |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S2661341723300033 |
| _version_ | 1797773531903164416 |
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| author | Carolyn Lee Chi Hung To |
| author_facet | Carolyn Lee Chi Hung To |
| author_sort | Carolyn Lee |
| collection | DOAJ |
| description | IgG4-related disease (IgG4-RD) is a multi-organ fibroinflammatory disorder that may result in organ dysfunction and complications. Glucocorticoids remain the primary treatment for inducing remission, while recently reported disease phenotypes might inform personalized therapeutic strategies. Progress in understanding the pathophysiology of IgG4-RD has led to the identification of novel treatment targets. Ongoing research will further refine the optimal treatment for IgG4-RD. This review offers an update on the latest evidence on the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of IgG4-RD. |
| first_indexed | 2024-03-12T22:07:50Z |
| format | Article |
| id | doaj.art-39a8d54b6ec9484a8ff4fffd55374ab4 |
| institution | Directory Open Access Journal |
| issn | 2661-3417 2661-3425 |
| language | English |
| last_indexed | 2024-03-12T22:07:50Z |
| publishDate | 2023-07-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Clinical Rheumatology and Immunology |
| spelling | doaj.art-39a8d54b6ec9484a8ff4fffd55374ab42023-07-24T09:11:50ZengWorld Scientific PublishingJournal of Clinical Rheumatology and Immunology2661-34172661-34252023-07-012301253410.1142/S2661341723300033IgG4-Related Disease: A Concise ReviewCarolyn Lee0Chi Hung To1Pok Oi Hospital, Hong Kong SAR, ChinaPok Oi Hospital, Hong Kong SAR, ChinaIgG4-related disease (IgG4-RD) is a multi-organ fibroinflammatory disorder that may result in organ dysfunction and complications. Glucocorticoids remain the primary treatment for inducing remission, while recently reported disease phenotypes might inform personalized therapeutic strategies. Progress in understanding the pathophysiology of IgG4-RD has led to the identification of novel treatment targets. Ongoing research will further refine the optimal treatment for IgG4-RD. This review offers an update on the latest evidence on the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of IgG4-RD.https://www.worldscientific.com/doi/10.1142/S2661341723300033IgG4-related DiseasePathophysiologyDiagnosisTreatment |
| spellingShingle | Carolyn Lee Chi Hung To IgG4-Related Disease: A Concise Review Journal of Clinical Rheumatology and Immunology IgG4-related Disease Pathophysiology Diagnosis Treatment |
| title | IgG4-Related Disease: A Concise Review |
| title_full | IgG4-Related Disease: A Concise Review |
| title_fullStr | IgG4-Related Disease: A Concise Review |
| title_full_unstemmed | IgG4-Related Disease: A Concise Review |
| title_short | IgG4-Related Disease: A Concise Review |
| title_sort | igg4 related disease a concise review |
| topic | IgG4-related Disease Pathophysiology Diagnosis Treatment |
| url | https://www.worldscientific.com/doi/10.1142/S2661341723300033 |
| work_keys_str_mv | AT carolynlee igg4relateddiseaseaconcisereview AT chihungto igg4relateddiseaseaconcisereview |