Identification of Disease-Related Genes That Are Common between Alzheimer’s and Cardiovascular Disease Using Blood Genome-Wide Transcriptome Analysis

Identification of Disease-Related Genes That Are Common between Alzheimer’s and Cardiovascular Disease Using Blood Genome-Wide Transcriptome Analysis

Accumulating evidence has suggested a shared pathophysiology between Alzheimer’s disease (AD) and cardiovascular disease (CVD). Based on genome-wide transcriptomes, specifically those of blood samples, we identify the shared disease-related signatures between AD and CVD. In addition to gene expressi...

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Bibliographic Details
Main Authors: Taesic Lee, Hyunju Lee, the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomedicines
Subjects:
Alzheimer’s disease
cardiovascular disease
blood gene expression
disease-related molecular signatures
differential expression analysis
gene regulatory network
Online Access:https://www.mdpi.com/2227-9059/9/11/1525

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