Shigella-mediated immunosuppression in the human gut: subversion extends from innate to adaptive immune responses

The enteropathogen, Shigella, is highly virulent and remarkably adjusted to the intestinal environment of its almost exclusive human host. Key for Shigella pathogenicity is the injection of virulence effectors into the host cell via its type three secretion system (T3SS), initiating disease onset an...

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Bibliographic Details
Main Authors: Katja Brunner, Fatoumata Samassa, Philippe J. Sansonetti, Armelle Phalipon
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2019.1594132