Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report

Severe positional obstructive sleep apnea syndrome (POSAS) is a common clinical respiratory disorder with an incidence of 26.7% to 74.5%. Continuous positive airway pressure (CPAP) combined with positional therapy is the gold standard of treatment. However, a mandibular advancement device (MAD) is a...

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Main Authors: Lucia Memè, Sabina Saccomanno, Enrico M. Strappa, Francesco Sampalmieri, Fabrizio Bambini, Gianni Gallusi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/20/10570
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author Lucia Memè
Sabina Saccomanno
Enrico M. Strappa
Francesco Sampalmieri
Fabrizio Bambini
Gianni Gallusi
author_facet Lucia Memè
Sabina Saccomanno
Enrico M. Strappa
Francesco Sampalmieri
Fabrizio Bambini
Gianni Gallusi
author_sort Lucia Memè
collection DOAJ
description Severe positional obstructive sleep apnea syndrome (POSAS) is a common clinical respiratory disorder with an incidence of 26.7% to 74.5%. Continuous positive airway pressure (CPAP) combined with positional therapy is the gold standard of treatment. However, a mandibular advancement device (MAD) is an effective alternative to CPAP when compliance with CPAP is low or if CPAP is rejected by the patient. A 63-year-old Caucasian male (BMI 26.1 kg/m<sup>2</sup>) complaining of repeated episodes of daytime sleepiness and heavy snoring was diagnosed with POSAS and treated with a MAD. After two years, polysomnographic (PSG) control analysis showed a significant reduction in the number of obstructive sleep apnea/hypopnea episodes per hour (AHI) by 58.9% in the lateral position and 75.5% in the supine position, complete remission of symptoms, a significant reduction in the severity of POSAS, and an overall improvement in quality of life. No adverse events or reduction in compliance were observed during the follow-up period. For severe POSAS, MADs may be an alternative method that is well tolerated by patients and has a good safety profile.
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spelling doaj.art-39b2ecac111b4155973f13d866c17a4d2023-11-23T22:46:51ZengMDPI AGApplied Sciences2076-34172022-10-0112201057010.3390/app122010570Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case ReportLucia Memè0Sabina Saccomanno1Enrico M. Strappa2Francesco Sampalmieri3Fabrizio Bambini4Gianni Gallusi5Department of Clinical Sciences and Stomatology, Polytechnic University of Marche, 60126 Ancona, ItalyDepartment of Health, Life and Environmental Science, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Health Technologies, IRCCS Orthopedic Institute Galeazzi, University of Milan, 20161 Milan, ItalyDepartment of Clinical Sciences and Stomatology, Polytechnic University of Marche, 60126 Ancona, ItalyDepartment of Clinical Sciences and Stomatology, Polytechnic University of Marche, 60126 Ancona, ItalyDepartment of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata”, 00133 Rome, ItalySevere positional obstructive sleep apnea syndrome (POSAS) is a common clinical respiratory disorder with an incidence of 26.7% to 74.5%. Continuous positive airway pressure (CPAP) combined with positional therapy is the gold standard of treatment. However, a mandibular advancement device (MAD) is an effective alternative to CPAP when compliance with CPAP is low or if CPAP is rejected by the patient. A 63-year-old Caucasian male (BMI 26.1 kg/m<sup>2</sup>) complaining of repeated episodes of daytime sleepiness and heavy snoring was diagnosed with POSAS and treated with a MAD. After two years, polysomnographic (PSG) control analysis showed a significant reduction in the number of obstructive sleep apnea/hypopnea episodes per hour (AHI) by 58.9% in the lateral position and 75.5% in the supine position, complete remission of symptoms, a significant reduction in the severity of POSAS, and an overall improvement in quality of life. No adverse events or reduction in compliance were observed during the follow-up period. For severe POSAS, MADs may be an alternative method that is well tolerated by patients and has a good safety profile.https://www.mdpi.com/2076-3417/12/20/10570obstructive sleep apnea syndromeoral appliancesmandibular advancement devicecontinuous positive airway pressuresevere OSASsnoring
spellingShingle Lucia Memè
Sabina Saccomanno
Enrico M. Strappa
Francesco Sampalmieri
Fabrizio Bambini
Gianni Gallusi
Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
Applied Sciences
obstructive sleep apnea syndrome
oral appliances
mandibular advancement device
continuous positive airway pressure
severe OSAS
snoring
title Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
title_full Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
title_fullStr Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
title_full_unstemmed Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
title_short Oral Appliances for Severe Positional Obstructive Sleep Apnea Syndrome: A Case Report
title_sort oral appliances for severe positional obstructive sleep apnea syndrome a case report
topic obstructive sleep apnea syndrome
oral appliances
mandibular advancement device
continuous positive airway pressure
severe OSAS
snoring
url https://www.mdpi.com/2076-3417/12/20/10570
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