Endobronchial tuberculosis polyps

Abstract Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobr...

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Main Authors: Christiaan Yu, Chuan Tai Foo, Ar Kar Aung, Simon A. Joosten
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.595
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author Christiaan Yu
Chuan Tai Foo
Ar Kar Aung
Simon A. Joosten
author_facet Christiaan Yu
Chuan Tai Foo
Ar Kar Aung
Simon A. Joosten
author_sort Christiaan Yu
collection DOAJ
description Abstract Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobronchial invasion, and nodular infiltrates in the right lower lobe. Flexible bronchoscopy revealed two endobronchial polyps at the carina and left main bronchus which were biopsied. Histopathology showed non‐caseating granulomas. Both the biopsy and bronchial washings did not identify acid‐fast bacilli on Ziehl‐Neelsen stain and had negative TB complex DNA polymerase chain reaction. One month after bronchoscopy, M. tuberculosis was cultured from the bronchial washings. Following six months of TB treatment, there was full resolution of symptoms and significant radiological improvement. We highlight the diagnostic challenges in endobronchial TB which may impact on the timely institution of treatment.
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spelling doaj.art-39b3c8d9f7c345dbbb543479e2a4a6d82022-12-21T18:41:46ZengWileyRespirology Case Reports2051-33802020-08-0186n/an/a10.1002/rcr2.595Endobronchial tuberculosis polypsChristiaan Yu0Chuan Tai Foo1Ar Kar Aung2Simon A. Joosten3Monash Lung and Sleep Monash Health Melbourne Victoria AustraliaMonash Lung and Sleep Monash Health Melbourne Victoria AustraliaSchool of Public Health and Preventative Medicine Monash University Melbourne Victoria AustraliaMonash Lung and Sleep Monash Health Melbourne Victoria AustraliaAbstract Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobronchial invasion, and nodular infiltrates in the right lower lobe. Flexible bronchoscopy revealed two endobronchial polyps at the carina and left main bronchus which were biopsied. Histopathology showed non‐caseating granulomas. Both the biopsy and bronchial washings did not identify acid‐fast bacilli on Ziehl‐Neelsen stain and had negative TB complex DNA polymerase chain reaction. One month after bronchoscopy, M. tuberculosis was cultured from the bronchial washings. Following six months of TB treatment, there was full resolution of symptoms and significant radiological improvement. We highlight the diagnostic challenges in endobronchial TB which may impact on the timely institution of treatment.https://doi.org/10.1002/rcr2.595Endobronchial polypsendobronchial tuberculosisflexible bronchoscopytuberculosis
spellingShingle Christiaan Yu
Chuan Tai Foo
Ar Kar Aung
Simon A. Joosten
Endobronchial tuberculosis polyps
Respirology Case Reports
Endobronchial polyps
endobronchial tuberculosis
flexible bronchoscopy
tuberculosis
title Endobronchial tuberculosis polyps
title_full Endobronchial tuberculosis polyps
title_fullStr Endobronchial tuberculosis polyps
title_full_unstemmed Endobronchial tuberculosis polyps
title_short Endobronchial tuberculosis polyps
title_sort endobronchial tuberculosis polyps
topic Endobronchial polyps
endobronchial tuberculosis
flexible bronchoscopy
tuberculosis
url https://doi.org/10.1002/rcr2.595
work_keys_str_mv AT christiaanyu endobronchialtuberculosispolyps
AT chuantaifoo endobronchialtuberculosispolyps
AT arkaraung endobronchialtuberculosispolyps
AT simonajoosten endobronchialtuberculosispolyps