Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells

Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells

Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, is an important public health problem mainly in Latin America, leading to approximately 12,000 annual deaths. Current etiological treatment for CD is limited to two nitro compounds, benznidazole (Bz...

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Bibliographic Details
Main Authors: Juliana Magalhães Chaves Barbosa, Yasmin Pedra-Rezende, Luíza Dantas Pereira, Tatiana Galvão de Melo, Helene Santos Barbosa, Joseli Lannes-Vieira, Solange Lisboa de Castro, Anissa Daliry, Kelly Salomão
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Trypanosoma cruzi
Chagas disease
amiodarone
benznidazole
combined treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.975931/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.975931/full

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