Profiling Human <i>CD55</i> Transgene Performance Assist in Selecting Best Suited Specimens and Tissues for Swine Organ Xenotransplantation

Profiling Human <i>CD55</i> Transgene Performance Assist in Selecting Best Suited Specimens and Tissues for Swine Organ Xenotransplantation

Xenotransplantation of pig organs receives substantial attention for being comparable to human’s. However, compatibility constraints involving hyper-acute rejection (HAR) still block clinical applications. Transgenesis of human complement regulatory proteins has been proposed to overcome xenorejecti...

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Bibliographic Details
Main Authors: Laura Martínez-Alarcón, Sergio Liarte, Juan J. Quereda, Aida Sáez-Acosta, Carlos de Torre-Minguela, Livia Mendonça, Juana M. Abellaneda, María J. Majado, Antonio Ríos, Pablo Ramírez, Antonio Muñoz, Guillermo Ramis
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
xenotransplantation
transgenic pigs
<i>hCD55</i>
RTCA
gene expression
Online Access:https://www.mdpi.com/2079-7737/10/8/747

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