A new inhibitor of apoptosis from vaccinia virus and eukaryotes.

A new apoptosis inhibitor is described from vaccinia virus, camelpox virus, and eukaryotic cells. The inhibitor is a hydrophobic, multiple transmembrane protein that is resident in the Golgi and is named GAAP (Golgi anti-apoptotic protein). Stable expression of both viral GAAP (v-GAAP) and human GAA...

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Bibliographic Details
Main Authors: Caroline Gubser, Daniele Bergamaschi, Michael Hollinshead, Xin Lu, Frank J M van Kuppeveld, Geoffrey L Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030017

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