A new inhibitor of apoptosis from vaccinia virus and eukaryotes.
A new apoptosis inhibitor is described from vaccinia virus, camelpox virus, and eukaryotic cells. The inhibitor is a hydrophobic, multiple transmembrane protein that is resident in the Golgi and is named GAAP (Golgi anti-apoptotic protein). Stable expression of both viral GAAP (v-GAAP) and human GAA...
Main Authors: | Caroline Gubser, Daniele Bergamaschi, Michael Hollinshead, Xin Lu, Frank J M van Kuppeveld, Geoffrey L Smith |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-02-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.0030017 |
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