Unveiling the mechanism of action of acylated temporin L analogues against multidrug-resistant Candida albicans

Unveiling the mechanism of action of acylated temporin L analogues against multidrug-resistant Candida albicans

AbstractThe increasing resistance of fungi to conventional antifungal drugs has prompted worldwide the search for new compounds. In this work, we investigated the antifungal properties of acylated Temporin L derivatives, Pent-1B and Dec-1B, against Candida albicans, including the multidrug-resistant...

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Bibliographic Details
Main Authors: Rosa Bellavita, Annarita Falanga, Francesco Merlino, Gabriella D’Auria, Nicola Molfetta, Anella Saviano, Francesco Maione, Umberto Galdiero, Maria Rosaria Catania, Stefania Galdiero, Paolo Grieco, Emanuela Roscetto, Lucia Falcigno, Elisabetta Buommino
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Acylated peptides
temporins
Candida albicans
membrane interaction
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2134359

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