Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation.
Cryptococcus neoformans is a fungal human pathogen with a bipolar mating system. It undergoes a dimorphic transition from a unicellular yeast to hyphal filamentous growth during mating and monokaryotic fruiting. The traditional sexual cycle that leads to the production of infectious basidiospores in...
Main Authors: | Xiaorong Lin, Johnny C Huang, Thomas G Mitchell, Joseph Heitman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-11-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1636697?pdf=render |
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