Surgical Management of Hereditary Breast Cancer
The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/12/9/1371 |
| _version_ | 1797519110978928640 |
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| author | Elizabeth R. Berger Mehra Golshan |
| author_facet | Elizabeth R. Berger Mehra Golshan |
| author_sort | Elizabeth R. Berger |
| collection | DOAJ |
| description | The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring surveillance, guiding decisions on medical or surgical risk reduction and cancer treatments for genetic variant carriers. This review discusses various medical and surgical management options for hereditary breast cancers. |
| first_indexed | 2024-03-10T07:38:30Z |
| format | Article |
| id | doaj.art-39c88cda780e4c90b03b66d657a24694 |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-10T07:38:30Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-39c88cda780e4c90b03b66d657a246942023-11-22T13:14:03ZengMDPI AGGenes2073-44252021-08-01129137110.3390/genes12091371Surgical Management of Hereditary Breast CancerElizabeth R. Berger0Mehra Golshan1Department of Surgery, School of Medicine, Yale University, New Haven, CT 06511, USADepartment of Surgery, School of Medicine, Yale University, New Haven, CT 06511, USAThe identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring surveillance, guiding decisions on medical or surgical risk reduction and cancer treatments for genetic variant carriers. This review discusses various medical and surgical management options for hereditary breast cancers.https://www.mdpi.com/2073-4425/12/9/1371hereditary breast cancergenetic variantsrisk reducing surgery |
| spellingShingle | Elizabeth R. Berger Mehra Golshan Surgical Management of Hereditary Breast Cancer Genes hereditary breast cancer genetic variants risk reducing surgery |
| title | Surgical Management of Hereditary Breast Cancer |
| title_full | Surgical Management of Hereditary Breast Cancer |
| title_fullStr | Surgical Management of Hereditary Breast Cancer |
| title_full_unstemmed | Surgical Management of Hereditary Breast Cancer |
| title_short | Surgical Management of Hereditary Breast Cancer |
| title_sort | surgical management of hereditary breast cancer |
| topic | hereditary breast cancer genetic variants risk reducing surgery |
| url | https://www.mdpi.com/2073-4425/12/9/1371 |
| work_keys_str_mv | AT elizabethrberger surgicalmanagementofhereditarybreastcancer AT mehragolshan surgicalmanagementofhereditarybreastcancer |