How I treat febrile neutropenia

The management of febrile neutropenia is a backbone of the treatment of patients with hematologic malignancies, and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients. Key topics discussed include antibacterial and anti...

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Main Author: Marcio Nucci
Format: Article
Language:English
Published: Mattioli1885 2021-02-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:https://www.mjhid.org/index.php/mjhid/article/view/4531
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author Marcio Nucci
author_facet Marcio Nucci
author_sort Marcio Nucci
collection DOAJ
description The management of febrile neutropenia is a backbone of the treatment of patients with hematologic malignancies, and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients. Key topics discussed include antibacterial and antifungal prophylaxis, the initial workup for fever, the choice of the empiric antibiotic regimen and its modifications, and criteria for discontinuation. For each of these questions, I review the literature and present my perspective.
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spelling doaj.art-39c9e547bcc24c70ae7f4329c19b76822022-12-21T17:23:31ZengMattioli1885Mediterranean Journal of Hematology and Infectious Diseases2035-30062021-02-0113110.4084/mjhid.2021.025How I treat febrile neutropeniaMarcio Nucci0M. Nucci, Hospital Universitário Clementino Fraga Filho, UFRJ. Rua Prof. Rodolpho Paulo Rocco 255 – 21941-913, Rio de Janeiro, Brazil E-mail: mnucci@hucff.ufrj.brThe management of febrile neutropenia is a backbone of the treatment of patients with hematologic malignancies, and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients. Key topics discussed include antibacterial and antifungal prophylaxis, the initial workup for fever, the choice of the empiric antibiotic regimen and its modifications, and criteria for discontinuation. For each of these questions, I review the literature and present my perspective.https://www.mjhid.org/index.php/mjhid/article/view/4531fever; neutropenia; febrile neutropenia; management
spellingShingle Marcio Nucci
How I treat febrile neutropenia
Mediterranean Journal of Hematology and Infectious Diseases
fever; neutropenia; febrile neutropenia; management
title How I treat febrile neutropenia
title_full How I treat febrile neutropenia
title_fullStr How I treat febrile neutropenia
title_full_unstemmed How I treat febrile neutropenia
title_short How I treat febrile neutropenia
title_sort how i treat febrile neutropenia
topic fever; neutropenia; febrile neutropenia; management
url https://www.mjhid.org/index.php/mjhid/article/view/4531
work_keys_str_mv AT marcionucci howitreatfebrileneutropenia