2-octynoic acid inhibits hepatitis C virus infection through activation of AMP-activated protein kinase.
Many chronic hepatitis C virus (HCV)-infected patients with current therapy do not clear the virus. It is necessary to find novel treatments. The effect of 2-octynoic acid (2-OA) on HCV infection in human hepatocytes was examined. The mechanism of 2-OA antiviral activity was explored. Our data showe...
| Main Authors: | , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Public Library of Science (PLoS)
2013-01-01
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| 叢編: | PLoS ONE |
| 在線閱讀: | http://europepmc.org/articles/PMC3669134?pdf=render |