Epilepsia experimental en pequeños animales
This work includes the chronic implantation of a nine electrode plug, on the skull of small animals, which had previously been treated as follows: one mi of aluminum oxide placed on the right anterior cerebral cortex. A pollyethylene tube was sometimes placed on each cerebral cortex to permit intrac...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
1964-10-01
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| Series: | Revista de la Facultad de Medicina |
| Subjects: | |
| Online Access: | https://revistas.unal.edu.co/index.php/revfacmed/article/view/22313 |
| _version_ | 1819072392547270656 |
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| author | Gerardo González C. F. de Balbian Verster A. Barros |
| author_facet | Gerardo González C. F. de Balbian Verster A. Barros |
| author_sort | Gerardo González C. |
| collection | DOAJ |
| description | This work includes the chronic implantation of a nine electrode plug, on the skull of small animals, which had previously been treated as follows: one mi of aluminum oxide placed on the right anterior cerebral cortex. A pollyethylene tube was sometimes placed on each cerebral cortex to permit intracraneal drug administration. E. E.G. recordings were made with unrestrained animals. 1. In the cortical area where the alumina had placed, an initial decrease in voltage was observed during the first four days. Four days later desynchronization of the background electrical activity increased voltage and localization of the primary focus were observed. 2. In the period from eight to twelve days after the alumina application, the animals developed an increased of voltage in the corresponding area of the contra lateral hemisphere. This corresponded to the development of a secondary or mirror" focus which was fully developed in about two days. its discharge at first depended on the primary focus but became independent in 10 to 15 days. 3. Two to three months after the alumina application, the electrical activity in the primary focus began to decrease and had disappeared almost completely after four months. 4. Any studies for the purpose of observing changes in electrical activity of the primary focus, should be done within the first three months after alumina application. On the other hand the secondary focus continues to fire for at least one year. |
| first_indexed | 2024-12-21T17:37:00Z |
| format | Article |
| id | doaj.art-39cf26fb7dae4d2eb42da2998287b6a9 |
| institution | Directory Open Access Journal |
| issn | 0120-0011 2357-3848 |
| language | English |
| last_indexed | 2024-12-21T17:37:00Z |
| publishDate | 1964-10-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista de la Facultad de Medicina |
| spelling | doaj.art-39cf26fb7dae4d2eb42da2998287b6a92022-12-21T18:55:44ZengUniversidad Nacional de ColombiaRevista de la Facultad de Medicina0120-00112357-38481964-10-013249910820042Epilepsia experimental en pequeños animalesGerardo González C.0F. de Balbian Verster1A. Barros2Universidad Nacional de ColombiaUniversidad Nacional de ColombiaUniversidad Nacional de ColombiaThis work includes the chronic implantation of a nine electrode plug, on the skull of small animals, which had previously been treated as follows: one mi of aluminum oxide placed on the right anterior cerebral cortex. A pollyethylene tube was sometimes placed on each cerebral cortex to permit intracraneal drug administration. E. E.G. recordings were made with unrestrained animals. 1. In the cortical area where the alumina had placed, an initial decrease in voltage was observed during the first four days. Four days later desynchronization of the background electrical activity increased voltage and localization of the primary focus were observed. 2. In the period from eight to twelve days after the alumina application, the animals developed an increased of voltage in the corresponding area of the contra lateral hemisphere. This corresponded to the development of a secondary or mirror" focus which was fully developed in about two days. its discharge at first depended on the primary focus but became independent in 10 to 15 days. 3. Two to three months after the alumina application, the electrical activity in the primary focus began to decrease and had disappeared almost completely after four months. 4. Any studies for the purpose of observing changes in electrical activity of the primary focus, should be done within the first three months after alumina application. On the other hand the secondary focus continues to fire for at least one year.https://revistas.unal.edu.co/index.php/revfacmed/article/view/22313epilepsia |
| spellingShingle | Gerardo González C. F. de Balbian Verster A. Barros Epilepsia experimental en pequeños animales Revista de la Facultad de Medicina epilepsia |
| title | Epilepsia experimental en pequeños animales |
| title_full | Epilepsia experimental en pequeños animales |
| title_fullStr | Epilepsia experimental en pequeños animales |
| title_full_unstemmed | Epilepsia experimental en pequeños animales |
| title_short | Epilepsia experimental en pequeños animales |
| title_sort | epilepsia experimental en pequenos animales |
| topic | epilepsia |
| url | https://revistas.unal.edu.co/index.php/revfacmed/article/view/22313 |
| work_keys_str_mv | AT gerardogonzalezc epilepsiaexperimentalenpequenosanimales AT fdebalbianverster epilepsiaexperimentalenpequenosanimales AT abarros epilepsiaexperimentalenpequenosanimales |