Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution
Throughout her impressive scientific career, Prof. María Vallet-Regí opened various research lines aimed at designing new bioceramics, including mesoporous bioactive glasses for bone tissue engineering applications. These bioactive glasses can be considered a spin-off of silica mesoporous materials...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/14/1/202 |
| _version_ | 1797491061209169920 |
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| author | Antonio J. Salinas Pedro Esbrit |
| author_facet | Antonio J. Salinas Pedro Esbrit |
| author_sort | Antonio J. Salinas |
| collection | DOAJ |
| description | Throughout her impressive scientific career, Prof. María Vallet-Regí opened various research lines aimed at designing new bioceramics, including mesoporous bioactive glasses for bone tissue engineering applications. These bioactive glasses can be considered a spin-off of silica mesoporous materials because they are designed with a similar technical approach. Mesoporous glasses in addition to SiO<sub>2</sub> contain significant amounts of other oxides, particularly CaO and P<sub>2</sub>O<sub>5</sub> and therefore, they exhibit quite different properties and clinical applications than mesoporous silica compounds. Both materials exhibit ordered mesoporous structures with a very narrow pore size distribution that are achieved by using surfactants during their synthesis. The characteristics of mesoporous glasses made them suitable to be enriched with various osteogenic agents, namely inorganic ions and biopeptides as well as mesenchymal cells. In the present review, we summarize the evolution of mesoporous bioactive glasses research for bone repair, with a special highlight on the impact of Prof. María Vallet-Regí´s contribution to the field. |
| first_indexed | 2024-03-10T00:41:56Z |
| format | Article |
| id | doaj.art-39d44530fcee4400bcf674e8c993c01e |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T00:41:56Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-39d44530fcee4400bcf674e8c993c01e2023-11-23T15:05:34ZengMDPI AGPharmaceutics1999-49232022-01-0114120210.3390/pharmaceutics14010202Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s ContributionAntonio J. Salinas0Pedro Esbrit1Departamento Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, UCM, Instituto de Investigación Hospital 12 de Octubre, imas12, 28040 Madrid, SpainDepartamento Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, UCM, Instituto de Investigación Hospital 12 de Octubre, imas12, 28040 Madrid, SpainThroughout her impressive scientific career, Prof. María Vallet-Regí opened various research lines aimed at designing new bioceramics, including mesoporous bioactive glasses for bone tissue engineering applications. These bioactive glasses can be considered a spin-off of silica mesoporous materials because they are designed with a similar technical approach. Mesoporous glasses in addition to SiO<sub>2</sub> contain significant amounts of other oxides, particularly CaO and P<sub>2</sub>O<sub>5</sub> and therefore, they exhibit quite different properties and clinical applications than mesoporous silica compounds. Both materials exhibit ordered mesoporous structures with a very narrow pore size distribution that are achieved by using surfactants during their synthesis. The characteristics of mesoporous glasses made them suitable to be enriched with various osteogenic agents, namely inorganic ions and biopeptides as well as mesenchymal cells. In the present review, we summarize the evolution of mesoporous bioactive glasses research for bone repair, with a special highlight on the impact of Prof. María Vallet-Regí´s contribution to the field.https://www.mdpi.com/1999-4923/14/1/202mesoporous bioactive glassesProf. Vallet-Regí: regenerative medicinebone repairtherapeutical ionsbioactive biomoleculesstem cells |
| spellingShingle | Antonio J. Salinas Pedro Esbrit Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution Pharmaceutics mesoporous bioactive glasses Prof. Vallet-Regí: regenerative medicine bone repair therapeutical ions bioactive biomolecules stem cells |
| title | Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution |
| title_full | Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution |
| title_fullStr | Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution |
| title_full_unstemmed | Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution |
| title_short | Mesoporous Bioglasses Enriched with Bioactive Agents for Bone Repair, with a Special Highlight of María Vallet-Regí’s Contribution |
| title_sort | mesoporous bioglasses enriched with bioactive agents for bone repair with a special highlight of maria vallet regi s contribution |
| topic | mesoporous bioactive glasses Prof. Vallet-Regí: regenerative medicine bone repair therapeutical ions bioactive biomolecules stem cells |
| url | https://www.mdpi.com/1999-4923/14/1/202 |
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