Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice.

Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice.

A single-injection vaccine formulation that provides for both a prime and a boost immunization would have various advantages over a multiple-injection regime. For such a vaccine formulation, it is essential that the booster dose is released after a certain, preferably adjustable, lag time. In this s...

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Bibliographic Details
Main Authors: Katie Amssoms, Philip A Born, Max Beugeling, Ben De Clerck, Ellen Van Gulck, Wouter L J Hinrichs, Henderik W Frijlink, Niels Grasmeijer, Guenter Kraus, Roger Sutmuller, Kenny Simmen, Lieven Baert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6117011?pdf=render

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