Absent phasing of respiratory and locomotor rhythms in running mice
Examining whether and how the rhythms of limb and breathing movements interact is highly informative about the mechanistic origin of hyperpnoea during running exercise. However, studies have failed to reveal regularities. In particular, whether breathing frequency is inherently proportional to limb...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2020-12-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/61919 |
| _version_ | 1818019542366945280 |
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| author | Coralie Hérent Séverine Diem Gilles Fortin Julien Bouvier |
| author_facet | Coralie Hérent Séverine Diem Gilles Fortin Julien Bouvier |
| author_sort | Coralie Hérent |
| collection | DOAJ |
| description | Examining whether and how the rhythms of limb and breathing movements interact is highly informative about the mechanistic origin of hyperpnoea during running exercise. However, studies have failed to reveal regularities. In particular, whether breathing frequency is inherently proportional to limb velocity and imposed by a synchronization of breaths to strides is still unclear. Here, we examined respiratory changes during running in the resourceful mouse model. We show that, for a wide range of trotting speeds on a treadmill, respiratory rate increases to a fixed and stable value irrespective of trotting velocities. Respiratory rate was yet further increased during escape-like running and most particularly at gallop. However, we found no temporal coordination of breaths to strides at any speed, intensity, or gait. Our work thus highlights that exercise hyperpnoea can operate, at least in mice and in the presently examined running regimes, without phasic constraints from limb movements. |
| first_indexed | 2024-04-14T07:52:31Z |
| format | Article |
| id | doaj.art-39da7fb94a554dcd8cb850fea9075c8f |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-14T07:52:31Z |
| publishDate | 2020-12-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-39da7fb94a554dcd8cb850fea9075c8f2022-12-22T02:05:08ZengeLife Sciences Publications LtdeLife2050-084X2020-12-01910.7554/eLife.61919Absent phasing of respiratory and locomotor rhythms in running miceCoralie Hérent0https://orcid.org/0000-0002-8472-5097Séverine Diem1Gilles Fortin2https://orcid.org/0000-0002-2123-8603Julien Bouvier3https://orcid.org/0000-0002-1307-4426Université Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Gif-sur-Yvette, FranceUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Gif-sur-Yvette, FranceInstitut de Biologie de l’École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, PSL Research University, Paris, FranceUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Gif-sur-Yvette, FranceExamining whether and how the rhythms of limb and breathing movements interact is highly informative about the mechanistic origin of hyperpnoea during running exercise. However, studies have failed to reveal regularities. In particular, whether breathing frequency is inherently proportional to limb velocity and imposed by a synchronization of breaths to strides is still unclear. Here, we examined respiratory changes during running in the resourceful mouse model. We show that, for a wide range of trotting speeds on a treadmill, respiratory rate increases to a fixed and stable value irrespective of trotting velocities. Respiratory rate was yet further increased during escape-like running and most particularly at gallop. However, we found no temporal coordination of breaths to strides at any speed, intensity, or gait. Our work thus highlights that exercise hyperpnoea can operate, at least in mice and in the presently examined running regimes, without phasic constraints from limb movements.https://elifesciences.org/articles/61919locomotionbreathingexercisegaitexercise physiology |
| spellingShingle | Coralie Hérent Séverine Diem Gilles Fortin Julien Bouvier Absent phasing of respiratory and locomotor rhythms in running mice eLife locomotion breathing exercise gait exercise physiology |
| title | Absent phasing of respiratory and locomotor rhythms in running mice |
| title_full | Absent phasing of respiratory and locomotor rhythms in running mice |
| title_fullStr | Absent phasing of respiratory and locomotor rhythms in running mice |
| title_full_unstemmed | Absent phasing of respiratory and locomotor rhythms in running mice |
| title_short | Absent phasing of respiratory and locomotor rhythms in running mice |
| title_sort | absent phasing of respiratory and locomotor rhythms in running mice |
| topic | locomotion breathing exercise gait exercise physiology |
| url | https://elifesciences.org/articles/61919 |
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