Metabolic engineering strategies to produce medium-chain oleochemicals via acyl-ACP:CoA transacylase activity

Microbial production of oleochemicals involves strategies of expressing thioesterase to narrow the substrate pool for the termination enzyme at the expense of one ATP. Here, the authors developed an alternative energy-efficient strategy to use of an acyl-ACP transacylase to produce medium chain oleo...

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Bibliographic Details
Main Authors: Qiang Yan, William T. Cordell, Michael A. Jindra, Dylan K. Courtney, Madeline K. Kuckuk, Xuanqi Chen, Brian F. Pfleger
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29218-3

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