KD025 (SLx-2119) suppresses adipogenesis at intermediate stage in human adipose-derived stem cells

KD025 (SLx-2119) suppresses adipogenesis at intermediate stage in human adipose-derived stem cells

Rho-associated kinases (ROCKs) have been reported to antagonize adipocyte differentiation, and inhibition of ROCKs by small molecules promotes adipogenesis. Surprisingly, our recent study revealed that the ROCK2-specific inhibitor KD025 (SLx-2119), suppresses differentiation at the intermediate stag...

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Bibliographic Details
Main Authors: Duy Trong Vien Diep, Khue Ha Minh Duong, Hojung Choi, Hee-Sook Jun, Kwang-Hoon Chun
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Adipocyte
Subjects:
kd025
slx-2119
adipogenesis
differentiation
rock
rho-associated kinase
Online Access:http://dx.doi.org/10.1080/21623945.2019.1590929

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