Imaging findings of mimickers of hepatocellular carcinoma
Radiological imaging plays a crucial role in the diagnosis of hepatocellular carcinoma (HCC) as the noninvasive diagnosis of HCC in high-risk patients by typical imaging findings alone is widely adopted in major practice guidelines for HCC. While imaging techniques have markedly improved in detectin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Association for the Study of the Liver
2015-12-01
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| Series: | Clinical and Molecular Hepatology |
| Subjects: | |
| Online Access: | http://e-cmh.org/upload/pdf/cmh-21-326.pdf |
| _version_ | 1819211619745398784 |
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| author | Tae Kyoung Kim Eunchae Lee Hyun-Jung Jang |
| author_facet | Tae Kyoung Kim Eunchae Lee Hyun-Jung Jang |
| author_sort | Tae Kyoung Kim |
| collection | DOAJ |
| description | Radiological imaging plays a crucial role in the diagnosis of hepatocellular carcinoma (HCC) as the noninvasive diagnosis of HCC in high-risk patients by typical imaging findings alone is widely adopted in major practice guidelines for HCC. While imaging techniques have markedly improved in detecting small liver lesions, they often detect incidental benign liver lesions and non-hepatocellular malignancy that can be misdiagnosed as HCC. The most common mimicker of HCC in cirrhotic liver is nontumorous arterioportal shunts that are seen as focal hypervascular liver lesions on dynamic contrast-enhanced cross-sectional imaging. Rapidly enhancing hemangiomas can be easily misdiagnosed as HCC especially on MR imaging with liver-specific contrast agent. Focal inflammatory liver lesions mimic HCC by demonstrating arterial-phase hypervascularity and subsequent washout on dynamic contrast-enhanced imaging. It is important to recognize the suggestive imaging findings for intrahepatic cholangiocarcinoma (CC) as the management of CC is largely different from that of HCC. There are other benign mimickers of HCC such as angiomyolipomas and focal nodular hyperplasia-like nodules. Recognition of their typical imaging findings can reduce false-positive HCC diagnosis. |
| first_indexed | 2024-12-23T06:29:57Z |
| format | Article |
| id | doaj.art-39e5130120374334a7a905561eb6e9eb |
| institution | Directory Open Access Journal |
| issn | 2287-2728 2287-285X |
| language | English |
| last_indexed | 2024-12-23T06:29:57Z |
| publishDate | 2015-12-01 |
| publisher | Korean Association for the Study of the Liver |
| record_format | Article |
| series | Clinical and Molecular Hepatology |
| spelling | doaj.art-39e5130120374334a7a905561eb6e9eb2022-12-21T17:56:58ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2015-12-0121432634310.3350/cmh.2015.21.4.3261160Imaging findings of mimickers of hepatocellular carcinomaTae Kyoung Kim0Eunchae Lee1Hyun-Jung Jang2Department of Medical Imaging, Toronto General Hospital, University of Toronto, Toronto, ON, Canada.Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Medical Imaging, Toronto General Hospital, University of Toronto, Toronto, ON, Canada.Radiological imaging plays a crucial role in the diagnosis of hepatocellular carcinoma (HCC) as the noninvasive diagnosis of HCC in high-risk patients by typical imaging findings alone is widely adopted in major practice guidelines for HCC. While imaging techniques have markedly improved in detecting small liver lesions, they often detect incidental benign liver lesions and non-hepatocellular malignancy that can be misdiagnosed as HCC. The most common mimicker of HCC in cirrhotic liver is nontumorous arterioportal shunts that are seen as focal hypervascular liver lesions on dynamic contrast-enhanced cross-sectional imaging. Rapidly enhancing hemangiomas can be easily misdiagnosed as HCC especially on MR imaging with liver-specific contrast agent. Focal inflammatory liver lesions mimic HCC by demonstrating arterial-phase hypervascularity and subsequent washout on dynamic contrast-enhanced imaging. It is important to recognize the suggestive imaging findings for intrahepatic cholangiocarcinoma (CC) as the management of CC is largely different from that of HCC. There are other benign mimickers of HCC such as angiomyolipomas and focal nodular hyperplasia-like nodules. Recognition of their typical imaging findings can reduce false-positive HCC diagnosis.http://e-cmh.org/upload/pdf/cmh-21-326.pdfCarcinoma, HepatocellularLiverDiagnostic imagingBenign neoplasms |
| spellingShingle | Tae Kyoung Kim Eunchae Lee Hyun-Jung Jang Imaging findings of mimickers of hepatocellular carcinoma Clinical and Molecular Hepatology Carcinoma, Hepatocellular Liver Diagnostic imaging Benign neoplasms |
| title | Imaging findings of mimickers of hepatocellular carcinoma |
| title_full | Imaging findings of mimickers of hepatocellular carcinoma |
| title_fullStr | Imaging findings of mimickers of hepatocellular carcinoma |
| title_full_unstemmed | Imaging findings of mimickers of hepatocellular carcinoma |
| title_short | Imaging findings of mimickers of hepatocellular carcinoma |
| title_sort | imaging findings of mimickers of hepatocellular carcinoma |
| topic | Carcinoma, Hepatocellular Liver Diagnostic imaging Benign neoplasms |
| url | http://e-cmh.org/upload/pdf/cmh-21-326.pdf |
| work_keys_str_mv | AT taekyoungkim imagingfindingsofmimickersofhepatocellularcarcinoma AT eunchaelee imagingfindingsofmimickersofhepatocellularcarcinoma AT hyunjungjang imagingfindingsofmimickersofhepatocellularcarcinoma |