Cancer Nanobombs Delivering Artoxplatin with a Polyigniter Bearing Hydrophobic Ferrocene Units Upregulate PD‐L1 Expression and Stimulate Stronger Anticancer Immunity

Cancer Nanobombs Delivering Artoxplatin with a Polyigniter Bearing Hydrophobic Ferrocene Units Upregulate PD‐L1 Expression and Stimulate Stronger Anticancer Immunity

Abstract Poor immunogenicity seriously hampers the broader implementation of antitumor immunotherapy. Enhanced immunogenicity capable of achieving greater antitumor immunity is urgently required. Here, a novel polymer that contains hydrophobic ferrocene (Fc) units and thioketal bonds in the main cha...

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Bibliographic Details
Main Authors: Yongchao Gao, Hanchen Zhang, Lin Tang, Feifei Li, Li Yang, Haihua Xiao, Johannes Karges, Weihua Huang, Wei Zhang, Chaoyong Liu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advanced Science
Subjects:
artoxplatin
chemo‐immunotherapy
immunogenic cell death
oxaliplatin
reactive oxygen species
Online Access:https://doi.org/10.1002/advs.202300806

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