Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism

Background. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glan...

Full description

Bibliographic Details
Main Authors: Tkachenko R.P., Kurik E.G., Gubar A.S., Belemets N.I.
Format: Article
Language:Russian
Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2014-06-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdf
_version_ 1811260408206458880
author Tkachenko R.P.
Kurik E.G.
Gubar A.S.
Belemets N.I.
author_facet Tkachenko R.P.
Kurik E.G.
Gubar A.S.
Belemets N.I.
author_sort Tkachenko R.P.
collection DOAJ
description Background. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glands, which are characteristic of tertiary hyperparathyroidism form. Intraoperative research of frozen sections allows to match of a similar macroscopic signs of external structures (parathyroid gland, thyroid gland, lymph node, fat, thymus) tissue is parathyroid glands. Objective. Aim – to research the morfhological features of parathyroid glands in secondary and tertiary hyperparathyroidism. Methods. The morphological features of parathyroid glands in 31 patients with secondary and tertiary hyperparathyroidism were studied. Results. Parathyroid hyperplasia – 4 cases (13%), nodulus hyperplasia (microadenoma) – 7 (22%) and parathyroid adenoma (more than 5 mm diameter) – 20 cases (65%) were found. Conclusion. In the most of parathyroid glands in secondary hyperparathyroidism we found the eadenomatous changes of gland parenchyma such as micro- and macroadenomatosis. Macroadenomas were observed in 2/3 cases that that testifies to passing of secondary hyperparathyroidism to tertiary hyperparathyroidism. Citation: Tkachenko RP, Kurik EG, Gubar AS, Belemets NI. [Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism]. Morphologia. 2014;8(2):67-71. Ukrainian.
first_indexed 2024-04-12T18:46:57Z
format Article
id doaj.art-39f252f5cda4409e80c9d7b2aef852fb
institution Directory Open Access Journal
issn 1997-9665
1997-9665
language Russian
last_indexed 2024-04-12T18:46:57Z
publishDate 2014-06-01
publisher Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
record_format Article
series Морфологія
spelling doaj.art-39f252f5cda4409e80c9d7b2aef852fb2022-12-22T03:20:35ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96651997-96652014-06-01826771Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidismTkachenko R.P.0Kurik E.G.1Gubar A.S.2Belemets N.I.3State Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, Kyiv; Bogomolets National Medical University, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivBackground. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glands, which are characteristic of tertiary hyperparathyroidism form. Intraoperative research of frozen sections allows to match of a similar macroscopic signs of external structures (parathyroid gland, thyroid gland, lymph node, fat, thymus) tissue is parathyroid glands. Objective. Aim – to research the morfhological features of parathyroid glands in secondary and tertiary hyperparathyroidism. Methods. The morphological features of parathyroid glands in 31 patients with secondary and tertiary hyperparathyroidism were studied. Results. Parathyroid hyperplasia – 4 cases (13%), nodulus hyperplasia (microadenoma) – 7 (22%) and parathyroid adenoma (more than 5 mm diameter) – 20 cases (65%) were found. Conclusion. In the most of parathyroid glands in secondary hyperparathyroidism we found the eadenomatous changes of gland parenchyma such as micro- and macroadenomatosis. Macroadenomas were observed in 2/3 cases that that testifies to passing of secondary hyperparathyroidism to tertiary hyperparathyroidism. Citation: Tkachenko RP, Kurik EG, Gubar AS, Belemets NI. [Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism]. Morphologia. 2014;8(2):67-71. Ukrainian.http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdfparathyroid glandssecondary hyperparathyroidismtertiary hyperparathyroidismmicroadenomatosisadenoma
spellingShingle Tkachenko R.P.
Kurik E.G.
Gubar A.S.
Belemets N.I.
Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
Морфологія
parathyroid glands
secondary hyperparathyroidism
tertiary hyperparathyroidism
microadenomatosis
adenoma
title Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
title_full Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
title_fullStr Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
title_full_unstemmed Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
title_short Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
title_sort pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
topic parathyroid glands
secondary hyperparathyroidism
tertiary hyperparathyroidism
microadenomatosis
adenoma
url http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdf
work_keys_str_mv AT tkachenkorp pathomorphologicalfeaturesofparathyroidglandsinsecondaryandtertiaryhyperparathyroidism
AT kurikeg pathomorphologicalfeaturesofparathyroidglandsinsecondaryandtertiaryhyperparathyroidism
AT gubaras pathomorphologicalfeaturesofparathyroidglandsinsecondaryandtertiaryhyperparathyroidism
AT belemetsni pathomorphologicalfeaturesofparathyroidglandsinsecondaryandtertiaryhyperparathyroidism