Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism
Background. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glan...
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Format: | Article |
Language: | Russian |
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Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
2014-06-01
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Series: | Морфологія |
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Online Access: | http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdf |
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author | Tkachenko R.P. Kurik E.G. Gubar A.S. Belemets N.I. |
author_facet | Tkachenko R.P. Kurik E.G. Gubar A.S. Belemets N.I. |
author_sort | Tkachenko R.P. |
collection | DOAJ |
description | Background. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glands, which are characteristic of tertiary hyperparathyroidism form. Intraoperative research of frozen sections allows to match of a similar macroscopic signs of external structures (parathyroid gland, thyroid gland, lymph node, fat, thymus) tissue is parathyroid glands. Objective. Aim – to research the morfhological features of parathyroid glands in secondary and tertiary hyperparathyroidism. Methods. The morphological features of parathyroid glands in 31 patients with secondary and tertiary hyperparathyroidism were studied. Results. Parathyroid hyperplasia – 4 cases (13%), nodulus hyperplasia (microadenoma) – 7 (22%) and parathyroid adenoma (more than 5 mm diameter) – 20 cases (65%) were found. Conclusion. In the most of parathyroid glands in secondary hyperparathyroidism we found the eadenomatous changes of gland parenchyma such as micro- and macroadenomatosis. Macroadenomas were observed in 2/3 cases that that testifies to passing of secondary hyperparathyroidism to tertiary hyperparathyroidism.
Citation: Tkachenko RP, Kurik EG, Gubar AS, Belemets NI. [Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism]. Morphologia. 2014;8(2):67-71. Ukrainian. |
first_indexed | 2024-04-12T18:46:57Z |
format | Article |
id | doaj.art-39f252f5cda4409e80c9d7b2aef852fb |
institution | Directory Open Access Journal |
issn | 1997-9665 1997-9665 |
language | Russian |
last_indexed | 2024-04-12T18:46:57Z |
publishDate | 2014-06-01 |
publisher | Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy |
record_format | Article |
series | Морфологія |
spelling | doaj.art-39f252f5cda4409e80c9d7b2aef852fb2022-12-22T03:20:35ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96651997-96652014-06-01826771Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidismTkachenko R.P.0Kurik E.G.1Gubar A.S.2Belemets N.I.3State Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, Kyiv; Bogomolets National Medical University, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivState Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of Public Administration, KyivBackground. Morphological methods of diagnosis in patients with secondary and tertiary hyperparathyroidism are very important, especially in the intraoperative and postoperative stages. In the end only able to detect microscopic examination microadenomatosis and macroadenomatosis of parathyroid glands, which are characteristic of tertiary hyperparathyroidism form. Intraoperative research of frozen sections allows to match of a similar macroscopic signs of external structures (parathyroid gland, thyroid gland, lymph node, fat, thymus) tissue is parathyroid glands. Objective. Aim – to research the morfhological features of parathyroid glands in secondary and tertiary hyperparathyroidism. Methods. The morphological features of parathyroid glands in 31 patients with secondary and tertiary hyperparathyroidism were studied. Results. Parathyroid hyperplasia – 4 cases (13%), nodulus hyperplasia (microadenoma) – 7 (22%) and parathyroid adenoma (more than 5 mm diameter) – 20 cases (65%) were found. Conclusion. In the most of parathyroid glands in secondary hyperparathyroidism we found the eadenomatous changes of gland parenchyma such as micro- and macroadenomatosis. Macroadenomas were observed in 2/3 cases that that testifies to passing of secondary hyperparathyroidism to tertiary hyperparathyroidism. Citation: Tkachenko RP, Kurik EG, Gubar AS, Belemets NI. [Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism]. Morphologia. 2014;8(2):67-71. Ukrainian.http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdfparathyroid glandssecondary hyperparathyroidismtertiary hyperparathyroidismmicroadenomatosisadenoma |
spellingShingle | Tkachenko R.P. Kurik E.G. Gubar A.S. Belemets N.I. Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism Морфологія parathyroid glands secondary hyperparathyroidism tertiary hyperparathyroidism microadenomatosis adenoma |
title | Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
title_full | Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
title_fullStr | Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
title_full_unstemmed | Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
title_short | Pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
title_sort | pathomorphological features of parathyroid glands in secondary and tertiary hyperparathyroidism |
topic | parathyroid glands secondary hyperparathyroidism tertiary hyperparathyroidism microadenomatosis adenoma |
url | http://www.morphology.dp.ua/_pub/MORPHO-2014-08-02/14trpvtg.pdf |
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