EF-Tu From Non-typeable Haemophilus influenzae Is an Immunogenic Surface-Exposed Protein Targeted by Bactericidal Antibodies

EF-Tu From Non-typeable Haemophilus influenzae Is an Immunogenic Surface-Exposed Protein Targeted by Bactericidal Antibodies

Non-typeable Haemophilus influenzae (NTHi), a commensal organism in pre-school children, is an opportunistic pathogen causing respiratory tract infections including acute otitis media. Adults suffering from chronic obstructive pulmonary disease (COPD) are persistently colonized by NTHi. Previous res...

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Bibliographic Details
Main Authors: Oskar Thofte, Yu-Ching Su, Marta Brant, Nils Littorin, Benjamin Luke Duell, Vera Alvarado, Farshid Jalalvand, Kristian Riesbeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
antibody response
elongation factor Tu (EF-Tu)
epitope mapping
Haemophilus influenzae (Hi)
immunization
rabbit
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02910/full

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