A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse

Aims: To evaluate the efficacy of Aloe Vera mouth rinse on experimental plaque accumulation and gingivitis. Materials and Methods: In this randomized, controlled, and double-blind study, a total of 148 systemically healthy subjects were screened in the age group of 18-25 years. Finally, 120 subjects...

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Main Authors: Bathini Chandrahas, Avula Jayakumar, Anumala Naveen, Kalakonda Butchibabu, Pathakota Krishnanjaneya Reddy, Tupili Muralikrishna
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2012;volume=16;issue=4;spage=543;epage=548;aulast=Chandrahas
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author Bathini Chandrahas
Avula Jayakumar
Anumala Naveen
Kalakonda Butchibabu
Pathakota Krishnanjaneya Reddy
Tupili Muralikrishna
author_facet Bathini Chandrahas
Avula Jayakumar
Anumala Naveen
Kalakonda Butchibabu
Pathakota Krishnanjaneya Reddy
Tupili Muralikrishna
author_sort Bathini Chandrahas
collection DOAJ
description Aims: To evaluate the efficacy of Aloe Vera mouth rinse on experimental plaque accumulation and gingivitis. Materials and Methods: In this randomized, controlled, and double-blind study, a total of 148 systemically healthy subjects were screened in the age group of 18-25 years. Finally, 120 subjects were requested to abstain from oral hygiene (tooth brushing) for 14 days and used a specially fabricated plaque guard. Following cessation of tooth brushing in the specified area, the subjects were randomly divided into Group A (test group) who received 100% Aloe vera, Group B (negative control group) who received placebo (distilled water), and Group C (positive control group) who received 0.2% chlorhexidine. The rinse regimen began on the 15 th day and continued for 7 days. Plaque accumulation was assessed by Plaque Index (PI) and gingivitis was assessed by Modified Gingival Index (MGI) and Bleeding Index (BI) at baseline (0), 7 th , 14 th , and 22 nd days. Results: There was statistically significant decrease in PI, MGI, and BI scores after the rinse regimen began in both Group A (test group) and Group C (chlorhexidine) compared with Group B. Mouth wash containing Aloe vera showed significant reduction of plaque and gingivitis but when compared with chlorhexidine the effect was less significant. Conclusion: Aloe vera mouthwash can be an effective antiplaque agent and with appropriate refinements in taste and shelf life can be an affordable herbal substitute for chlorhexidine.
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spelling doaj.art-39f961c405bc4f3fa8c05d5c47e612dc2022-12-22T02:52:02ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2012-01-0116454354810.4103/0972-124X.106905A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinseBathini ChandrahasAvula JayakumarAnumala NaveenKalakonda ButchibabuPathakota Krishnanjaneya ReddyTupili MuralikrishnaAims: To evaluate the efficacy of Aloe Vera mouth rinse on experimental plaque accumulation and gingivitis. Materials and Methods: In this randomized, controlled, and double-blind study, a total of 148 systemically healthy subjects were screened in the age group of 18-25 years. Finally, 120 subjects were requested to abstain from oral hygiene (tooth brushing) for 14 days and used a specially fabricated plaque guard. Following cessation of tooth brushing in the specified area, the subjects were randomly divided into Group A (test group) who received 100% Aloe vera, Group B (negative control group) who received placebo (distilled water), and Group C (positive control group) who received 0.2% chlorhexidine. The rinse regimen began on the 15 th day and continued for 7 days. Plaque accumulation was assessed by Plaque Index (PI) and gingivitis was assessed by Modified Gingival Index (MGI) and Bleeding Index (BI) at baseline (0), 7 th , 14 th , and 22 nd days. Results: There was statistically significant decrease in PI, MGI, and BI scores after the rinse regimen began in both Group A (test group) and Group C (chlorhexidine) compared with Group B. Mouth wash containing Aloe vera showed significant reduction of plaque and gingivitis but when compared with chlorhexidine the effect was less significant. Conclusion: Aloe vera mouthwash can be an effective antiplaque agent and with appropriate refinements in taste and shelf life can be an affordable herbal substitute for chlorhexidine.http://www.jisponline.com/article.asp?issn=0972-124X;year=2012;volume=16;issue=4;spage=543;epage=548;aulast=ChandrahasAloe verachlorhexidinegingivitisplaqueplaque guard
spellingShingle Bathini Chandrahas
Avula Jayakumar
Anumala Naveen
Kalakonda Butchibabu
Pathakota Krishnanjaneya Reddy
Tupili Muralikrishna
A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
Journal of Indian Society of Periodontology
Aloe vera
chlorhexidine
gingivitis
plaque
plaque guard
title A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
title_full A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
title_fullStr A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
title_full_unstemmed A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
title_short A randomized, double‑blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse
title_sort randomized double blind clinical study to assess the antiplaque and antigingivitis efficacy of aloe vera mouth rinse
topic Aloe vera
chlorhexidine
gingivitis
plaque
plaque guard
url http://www.jisponline.com/article.asp?issn=0972-124X;year=2012;volume=16;issue=4;spage=543;epage=548;aulast=Chandrahas
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