Robust mitotic entry is ensured by a latching switch

Robust mitotic entry is ensured by a latching switch

Summary Cell cycle events are driven by Cyclin dependent kinases (CDKs) and by their counter-acting phosphatases. Activation of the Cdk1:Cyclin B complex during mitotic entry is controlled by the Wee1/Myt1 inhibitory kinases and by Cdc25 activatory phosphatase, which are themselves regulated by Cdk1...

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Bibliographic Details
Main Authors: Chloe Tuck, Tongli Zhang, Tamara Potapova, Marcos Malumbres, Béla Novák
Format: Article
Language:English
Published: The Company of Biologists 2013-07-01
Series:Biology Open
Subjects:
G2/M transition
Mitotic entry
Mitotic collapse
Greatwall kinase
Spatial control of mitosis
Cell cycle
Online Access:http://bio.biologists.org/content/2/9/924

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