Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review

Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review

The blood-brain barrier (BBB), which is composed of endothelial cells, pericytes, astrocytes, and neurons, separates the brain extracellular fluid from the circulating blood, and maintains the homeostasis of the central nervous system (CNS). The BBB endothelial cells have well-developed tight juncti...

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Bibliographic Details
Main Authors: Keisuke Tachibana, Yumi Iwashita, Erika Wakayama, Itsuki Nishino, Taiki Nishikaji, Masuo Kondoh
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pharmaceutics
Subjects:
blood-brain barrier (BBB)
tight junction (TJ)
claudin
angulin
angubindin-1
antibody
Online Access:https://www.mdpi.com/1999-4923/12/12/1236

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