Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse
Case summary A 1-year-old male castrated domestic shorthair cat was presented to the Ontario Veterinary College for a week-long history of lethargy and reluctance to walk. CT and MRI revealed a monostotic T5 compressive vertebral lesion that was excised in surgery via pediculectomy. Histology and ad...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-02-01
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| Series: | Journal of Feline Medicine and Surgery Open Reports |
| Online Access: | https://doi.org/10.1177/20551169231155062 |
| _version_ | 1797894723106504704 |
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| author | Hugo Leonardi Valérie Poirier Melanie Iverson Francesca Samarani |
| author_facet | Hugo Leonardi Valérie Poirier Melanie Iverson Francesca Samarani |
| author_sort | Hugo Leonardi |
| collection | DOAJ |
| description | Case summary A 1-year-old male castrated domestic shorthair cat was presented to the Ontario Veterinary College for a week-long history of lethargy and reluctance to walk. CT and MRI revealed a monostotic T5 compressive vertebral lesion that was excised in surgery via pediculectomy. Histology and advanced imaging were consistent with feline vertebral angiomatosis. The cat relapsed both clinically and on CT 2 months postoperatively and was therefore treated with an intensity-modulated radiation therapy protocol (45 Gy over 18 fractions) and tapering doses of prednisolone. On follow-up CT and MRI at 3 and 6 months post-radiation, the lesion was static and then improved at 19 months post-radiation, with no signs of pain reported. Relevance and novel information To our knowledge, this is the first described case of a postoperative relapse of feline vertebral angiomatosis treated with radiation therapy and prednisolone with a successful long-term follow-up. |
| first_indexed | 2024-04-10T07:14:56Z |
| format | Article |
| id | doaj.art-39ff0e0839dc4cdf948a9ff4c24b935c |
| institution | Directory Open Access Journal |
| issn | 2055-1169 |
| language | English |
| last_indexed | 2024-04-10T07:14:56Z |
| publishDate | 2023-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Feline Medicine and Surgery Open Reports |
| spelling | doaj.art-39ff0e0839dc4cdf948a9ff4c24b935c2023-02-25T21:33:18ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692023-02-01910.1177/20551169231155062Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapseHugo Leonardi0Valérie Poirier1Melanie Iverson2Francesca Samarani3Department of Neurology, Azurvet, Saint-Laurent du Var, FranceDepartment of Clinical Studies, University of Guelph, Ontario Veterinary College (OVC), Guelph, ON, CanadaDepartment of Pathobiology, University of Guelph, Ontario Veterinary College (OVC), Guelph, ON, CanadaDepartment of Clinical Studies, University of Guelph, Ontario Veterinary College (OVC), Guelph, ON, CanadaCase summary A 1-year-old male castrated domestic shorthair cat was presented to the Ontario Veterinary College for a week-long history of lethargy and reluctance to walk. CT and MRI revealed a monostotic T5 compressive vertebral lesion that was excised in surgery via pediculectomy. Histology and advanced imaging were consistent with feline vertebral angiomatosis. The cat relapsed both clinically and on CT 2 months postoperatively and was therefore treated with an intensity-modulated radiation therapy protocol (45 Gy over 18 fractions) and tapering doses of prednisolone. On follow-up CT and MRI at 3 and 6 months post-radiation, the lesion was static and then improved at 19 months post-radiation, with no signs of pain reported. Relevance and novel information To our knowledge, this is the first described case of a postoperative relapse of feline vertebral angiomatosis treated with radiation therapy and prednisolone with a successful long-term follow-up.https://doi.org/10.1177/20551169231155062 |
| spellingShingle | Hugo Leonardi Valérie Poirier Melanie Iverson Francesca Samarani Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse Journal of Feline Medicine and Surgery Open Reports |
| title | Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| title_full | Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| title_fullStr | Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| title_full_unstemmed | Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| title_short | Successful long-term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| title_sort | successful long term outcome with radiation and prednisolone following a postoperative feline vertebral angiomatosis relapse |
| url | https://doi.org/10.1177/20551169231155062 |
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