Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population

Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population

Abstract Background Susceptibility to Chronic Myeloid Leukemia (CML) may be modulated by genetic variables. However, the majority of previous investigations have focused on genetically homogeneous populations, resulting in a lack of evidence on how genetic factors may influence the development of CM...

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Bibliographic Details
Main Authors: Natasha Monte, Karla B. C. C. Pantoja, Juliana C. G. Rodrigues, Darlen C. deCarvalho, Tereza C. B. Azevedo, Esdras E. B. Pereira, Paulo P. deAssumpção, Sidney E. B. dosSantos, Marianne R. Fernandes, Ney P. C. dosSantos
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
ABCC4
ancestry
chronic myeloid leukemia
CYP2A6
genetic susceptibility
Online Access:https://doi.org/10.1002/mgg3.1694

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