Enhanced osteogenic differentiation of alendronate-conjugated nanodiamonds for potential osteoporosis treatment

Enhanced osteogenic differentiation of alendronate-conjugated nanodiamonds for potential osteoporosis treatment

Abstract Background Alendronate (Alen) is promising material used for bone-targeted drug delivery due to its high bone affinity and therapeutic effects on bone diseases. In addition, Alen can enhance the osteogenic differentiation of osteoblastic cell. Recently, nanodiamonds (NDs) with hardness, non...

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Bibliographic Details
Main Authors: Guk Young Ahn, Sung-Eun Kim, Tae Hoon Yun, Inseong Choi, Daewon Park, Sung-Wook Choi
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021-09-01
Series:Biomaterials Research
Subjects:
Alendronate
Nanodiamond
Proliferation
Osteogenic differentiation
Online Access:https://doi.org/10.1186/s40824-021-00231-9

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