Regenerating hair cells in vestibular sensory epithelia from humans

Regenerating hair cells in vestibular sensory epithelia from humans

Human vestibular sensory epithelia in explant culture were incubated in gentamicin to ablate hair cells. Subsequent transduction of supporting cells with ATOH1 using an Ad-2 viral vector resulted in generation of highly significant numbers of cells expressing the hair cell marker protein myosin VIIa...

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Bibliographic Details
Main Authors: Ruth Rebecca Taylor, Anastasia Filia, Ursula Paredes, Yukako Asai, Jeffrey R Holt, Michael Lovett, Andrew Forge
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
hair cells
regeneration
vestibular
transcriptomics
Online Access:https://elifesciences.org/articles/34817

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