In Vitro Evaluation of ALDH1A3-Affinic Compounds on Breast and Prostate Cancer Cell Lines as Single Treatments and in Combination with Doxorubicin

In Vitro Evaluation of ALDH1A3-Affinic Compounds on Breast and Prostate Cancer Cell Lines as Single Treatments and in Combination with Doxorubicin

Aldehyde dehydrogenase (ALDH) enzymes are involved in the growth and development of several tissues, including cancer cells. It has been reported that targeting the ALDH family, including the ALDH1A subfamily, enhances cancer treatment outcomes. Therefore, we aimed to investigate the cytotoxicity of...

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Bibliographic Details
Main Authors: Osama H. Abusara, Ali I. M. Ibrahim, Hamzah Issa, Alaa M. Hammad, Worood H. Ismail
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Current Issues in Molecular Biology
Subjects:
ALDH inhibitors
doxorubicin
combination treatment
breast cancer
prostate cancer
Online Access:https://www.mdpi.com/1467-3045/45/3/139

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