The Significance of NLRP Inflammasome in Neuropsychiatric Disorders

The Significance of NLRP Inflammasome in Neuropsychiatric Disorders

The NLRP inflammasome is a multi-protein complex which mainly consists of the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain. Its activation is linked to microglial-mediated neuroinflammation and partial neuronal degeneration. Many neuropsychiatric illnesses have in...

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Bibliographic Details
Main Authors: Yao Shen, Liyin Qian, Hu Luo, Xiaofang Li, Yuer Ruan, Runyue Fan, Zizhen Si, Yunpeng Chen, Longhui Li, Yu Liu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Brain Sciences
Subjects:
NLRP inflammasome
neuropsychiatric disorders
neuroinflammation
pharmacological treatment
Online Access:https://www.mdpi.com/2076-3425/12/8/1057

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