RXFP1 is targeted by complement C1q Tumor Necrosis Factor-related factor 8 (CTRP8) in brain cancer

RXFP1 is targeted by complement C1q Tumor Necrosis Factor-related factor 8 (CTRP8) in brain cancer

The relaxin-like - RXFP1 ligand-receptor system has important functions in tumor growth and tissue invasion. Recently, we have identified the secreted protein, CTRP8, a member of the C1q/ Tumor Necrosis Factor-related protein (CTRP) family, as a novel ligand of the relaxin receptor RXFP1 with functi...

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Bibliographic Details
Main Authors: Thatchawan eThanasupawat, Aleksandra eGlogowska, Maxwell eBurg, William G. Wong, Cuong eHoang-Vu, Sabine eHombach-Klonisch, Thomas eKlonisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Endocrinology
Subjects:
Cancer
brain tumor
RXFP1
CTRP8
C1q/TNF-related proteins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00127/full

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