Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience
BackgroundSome deficiencies and shortcomings in treatment strategies of brain arteriovenous malformation (bAVM) remain. It is worth exploring whether the one-stop hybrid surgical platform can play a positive role in the treatment of bAVM.ObjectiveThis study investigated short clinical and angiograph...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.1052882/full |
| _version_ | 1811244261133254656 |
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| author | Wei Fang Zijian Yang Yufeng Liu Jia Yu Peng Sun Zhenwei Zhao Yue He Tao Zhang Jianping Deng |
| author_facet | Wei Fang Zijian Yang Yufeng Liu Jia Yu Peng Sun Zhenwei Zhao Yue He Tao Zhang Jianping Deng |
| author_sort | Wei Fang |
| collection | DOAJ |
| description | BackgroundSome deficiencies and shortcomings in treatment strategies of brain arteriovenous malformation (bAVM) remain. It is worth exploring whether the one-stop hybrid surgical platform can play a positive role in the treatment of bAVM.ObjectiveThis study investigated short clinical and angiographic results of one-stop hybrid surgery for the treatment of bAVM.MethodsAll patients with bAVM treated with one-stop hybrid surgery were reviewed from February 2017 to December 2021. Data including demographic information, clinical conditions, characteristics of AVM, procedure details, and clinical and angiographic results were collected.ResultIn total, 150 cerebral bAVM patients received one-stop hybrid surgery; among them, 122 received surgical resection assisted by intraoperative DSA, and 28 were treated with combination surgical resection and endovascular embolization. Complete angiographic obliteration of the AVM was achieved in 136 patients (90.7%), and procedure-related death and neurological deficit rates were 7.3%. Of all relevant variables, logistic regression analysis showed that the Spetzler & Martin (S&M) score was the only factor related to the cure rate (P < 0.001) and endpoint complication rate (P = 0.007).ConclusionsIn our preliminary experience, one-stop hybrid surgery for the treatment of brain AVMs achieves a high angiographic total occlusion rate, with acceptable peri-procedure morbidity and mortality. For S&M 4 and 5 lesions, more cases and further study are needed to investigate the effects and safety of hybrid surgery. |
| first_indexed | 2024-04-12T14:22:52Z |
| format | Article |
| id | doaj.art-3a10fff437bf4c668c5e957781b63d66 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-12T14:22:52Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-3a10fff437bf4c668c5e957781b63d662022-12-22T03:29:32ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-11-011310.3389/fneur.2022.10528821052882Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experienceWei Fang0Zijian Yang1Yufeng Liu2Jia Yu3Peng Sun4Zhenwei Zhao5Yue He6Tao Zhang7Jianping Deng8Department of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaTongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, ChinaBackgroundSome deficiencies and shortcomings in treatment strategies of brain arteriovenous malformation (bAVM) remain. It is worth exploring whether the one-stop hybrid surgical platform can play a positive role in the treatment of bAVM.ObjectiveThis study investigated short clinical and angiographic results of one-stop hybrid surgery for the treatment of bAVM.MethodsAll patients with bAVM treated with one-stop hybrid surgery were reviewed from February 2017 to December 2021. Data including demographic information, clinical conditions, characteristics of AVM, procedure details, and clinical and angiographic results were collected.ResultIn total, 150 cerebral bAVM patients received one-stop hybrid surgery; among them, 122 received surgical resection assisted by intraoperative DSA, and 28 were treated with combination surgical resection and endovascular embolization. Complete angiographic obliteration of the AVM was achieved in 136 patients (90.7%), and procedure-related death and neurological deficit rates were 7.3%. Of all relevant variables, logistic regression analysis showed that the Spetzler & Martin (S&M) score was the only factor related to the cure rate (P < 0.001) and endpoint complication rate (P = 0.007).ConclusionsIn our preliminary experience, one-stop hybrid surgery for the treatment of brain AVMs achieves a high angiographic total occlusion rate, with acceptable peri-procedure morbidity and mortality. For S&M 4 and 5 lesions, more cases and further study are needed to investigate the effects and safety of hybrid surgery.https://www.frontiersin.org/articles/10.3389/fneur.2022.1052882/fullcerebral arteriovenous malformation (AVM)endovascular treatmenthybrid surgeryintraoperative angiographymicrosurgical treatment |
| spellingShingle | Wei Fang Zijian Yang Yufeng Liu Jia Yu Peng Sun Zhenwei Zhao Yue He Tao Zhang Jianping Deng Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience Frontiers in Neurology cerebral arteriovenous malformation (AVM) endovascular treatment hybrid surgery intraoperative angiography microsurgical treatment |
| title | Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience |
| title_full | Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience |
| title_fullStr | Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience |
| title_full_unstemmed | Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience |
| title_short | Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience |
| title_sort | peri procedure efficacy and safety of one stop hybrid surgery for the treatment of brain arteriovenous malformations a single center preliminary experience |
| topic | cerebral arteriovenous malformation (AVM) endovascular treatment hybrid surgery intraoperative angiography microsurgical treatment |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.1052882/full |
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