Promotion or remission: a role of noncoding RNAs in colorectal cancer resistance to anti-EGFR therapy

Promotion or remission: a role of noncoding RNAs in colorectal cancer resistance to anti-EGFR therapy

Abstract Anti-epidermal-growth-factor-receptor (EGFR) monoclonal antibodies (mAbs) are of great significance for RAS and BRAF wild-type metastatic colorectal cancer (mCRC) patients. However, the generation of primary and secondary resistance to anti-EGFR mAbs has become an important factor restricti...

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Bibliographic Details
Main Authors: Shanshan Wei, Wenwei Hu, Jun Feng, Yiting Geng
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cell Communication and Signaling
Subjects:
Anti-EGFR monoclonal antibody
Colorectal cancer
Resistance
ncRNA
lncRNA
miRNA
Online Access:https://doi.org/10.1186/s12964-022-00960-x

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