A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using <i>Leishmania donovani</i>

A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using <i>Leishmania donovani</i>

Metals have been used in medicine since ancient times for the treatment of different ailments with various elements such as iron, gold and arsenic. Metal complexes have also been reported to show antibiotic and antiparasitic activity. In this context, we tested the antiparasitic potential of 10 orga...

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Bibliographic Details
Main Authors: Obaid Hayat, Nazif Ullah, Muhammad Sirajuddin, Miriam A. Giardini, Jennifer V. Nguyen, Karol R. Francisco, Lawrence J. Liu, Yujie Uli Sun, Svetlana Maurya, Dominic McGrosso, David J. Gonzalez, Conor R. Caffrey, Anjan Debnath, Jair L. Siqueira-Neto
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pathogens
Subjects:
organotin (IV) compounds
antiparasitic activity
neglected tropical diseases
drug discovery
Online Access:https://www.mdpi.com/2076-0817/11/12/1424

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