Tools to measure membrane potential of neurons

The brain is the most unexplored part of our body. The lack of sufficient tools has hindered our understanding of the brain and the associated diseases. The study of neurons and the neuronal network will help elucidate how the brain functions and related disorders. Over the last few decades, an incr...

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Main Author: Anjul Khadria
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417022000920
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author Anjul Khadria
author_facet Anjul Khadria
author_sort Anjul Khadria
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description The brain is the most unexplored part of our body. The lack of sufficient tools has hindered our understanding of the brain and the associated diseases. The study of neurons and the neuronal network will help elucidate how the brain functions and related disorders. Over the last few decades, an increasing number of techniques have been reported to study neurons and neuronal communication in vitro, ex vivo, and in vivo. These methods have pushed the boundaries of neuroscience and elucidated more information than ever before; however, much more requires to be done to understand the brain in its entirety. In this review article, I discuss the principles and the advantages and disadvantages of the classical electrode-based recording techniques and the optical imaging-based methods, which have aided neuroscientists in understanding neuronal communication.
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spelling doaj.art-3a13e12f180346e4b373d286467c0e942022-12-22T02:29:59ZengElsevierBiomedical Journal2319-41702022-10-01455749762Tools to measure membrane potential of neuronsAnjul Khadria0Corresponding author. Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology; Pasadena, California, 91125, USA.; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UKThe brain is the most unexplored part of our body. The lack of sufficient tools has hindered our understanding of the brain and the associated diseases. The study of neurons and the neuronal network will help elucidate how the brain functions and related disorders. Over the last few decades, an increasing number of techniques have been reported to study neurons and neuronal communication in vitro, ex vivo, and in vivo. These methods have pushed the boundaries of neuroscience and elucidated more information than ever before; however, much more requires to be done to understand the brain in its entirety. In this review article, I discuss the principles and the advantages and disadvantages of the classical electrode-based recording techniques and the optical imaging-based methods, which have aided neuroscientists in understanding neuronal communication.http://www.sciencedirect.com/science/article/pii/S2319417022000920Action potentialMembrane potentialNeuronsVoltage-sensitive dyesBrain
spellingShingle Anjul Khadria
Tools to measure membrane potential of neurons
Biomedical Journal
Action potential
Membrane potential
Neurons
Voltage-sensitive dyes
Brain
title Tools to measure membrane potential of neurons
title_full Tools to measure membrane potential of neurons
title_fullStr Tools to measure membrane potential of neurons
title_full_unstemmed Tools to measure membrane potential of neurons
title_short Tools to measure membrane potential of neurons
title_sort tools to measure membrane potential of neurons
topic Action potential
Membrane potential
Neurons
Voltage-sensitive dyes
Brain
url http://www.sciencedirect.com/science/article/pii/S2319417022000920
work_keys_str_mv AT anjulkhadria toolstomeasuremembranepotentialofneurons